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Applexion IER Decolorization Technologies
Chromatography
Chromatography is a technique for separating molecules in a liquid mixture using a stationary phase, here resin beads.
The molecules will be separated according to their difference of affinity with the resin resulting on a difference of speed through the system. Because it’s based on affinity difference, it aims to separate compounds without regenerant use (means without chemicals classically used for regeneration). This technology is commonly used at laboratory scale for analyses but also at industrial scale for food, pharma and biotech industries.
Ion exchange and adsorption
Ion exchange (IEX) is a mechanism that removes ions or other compounds, often considered as impurities, from a liquid solution by exchanging them with ions of similar charge on a resin through a reversible interchange. This basic principle involves the use of an ion exchange resin, which is a polymer matrix containing functional groups capable of linking and exchanging ions. Adsorption is a mechanism for separating molecules from a liquid mixture using the capacity of a porous resin to link reversibly with certain molecules in particular.
Cross flow filtration
Membrane filtration is a purification process used to separate particles from soluble compounds in a liquid flow, based on their physical size, which is very often closely correlated to their molecular weight . With cross flow filtration (CFF), also called tangential flow filtration (TFF), the fluid flows tangentially to the filtration membrane and only a portion will flow across thanks to the pressure applied, instead of having all the flow frontally passing through, while particle would accumulate at the surface of the media.
